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Rheumatoid Arthritis News
FDA Approves Tocilizumab for Treatment of Rheumatoid Arthritis
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High Disease Activity During Pregnancy Associated with Lower Birth Weight
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Surveillance Study Reports No Increase in Cancer Risk Over First Six years of TNF Inhibitor Use
While most observational studies have not demonstrated an increase in malignancy independently associated with TNF inhibitor use, a meta-analysis of short-term clinical trials data suggested an increase in malignancy risk occurring within months of initiating therapy with monoclonal antibodies directed against TNF-α (infliximab and adalimumab).
Swefot Trial Suggests Adding TNF Inhibitor Better than Triple Therapy in RA Patients who do not Rapidly Respond to Methotrexate
Initial combination therapy has been shown to be superior to step-up combination therapy in groups of RA patients; however, these findings are difficult to reconcile with the observation that many RA patients will have complete remission of disease on methotrexate alone. Practice patterns tend to emphasize initial treatment with methotrexate monotherapy, followed by the addition of other agents in combination for those with inadequate responses.
Effectiveness of Tai Chi for Musculoskeletal Pain Reviewed
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