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Cytokine Traps: Novel Anti-Cytokine Blockers
…and rapid clearance in vivo. IL-1 (like IL-4 and IL-6) uses a complex multi-component receptor system in which IL-1 binds with low affinity to the first receptor component (IL-1receptor type…
No Link Between RA Therapy and Lymphoma Observed in Large Cohort of Rheumatoid Arthritis Patients
…including RA medications and incident comorbidities (such as new lymphoma diagnosis). Reports of incident lymphomas were confirmed with medical records. Incidence rates for lymphoma in RA subjects were compared to…
Is There an Association Between Carotid Atherosclerosis and Inflammatory Markers in RA Patients from Johns Hopkins Arthritis
…IMT or prevalence of carotid plaque was seen between RA subjects compared to non-RA controls. Editorial Comments: A number of published studies, including one by these same investigators, have shown…
Is There an Increased Risk of Malignancy and Serious Infection Among RA patients Receiving High-dose Anti-TNF Therapy?
…treated patients compared to placebo treated patients from the combined data set. Results: Nine trials met inclusion criteria, comprising 5014 patients randomized to receive adalimumab or infliximab (n=3493) or placebo…
Pregnancy Outcomes in Patients with Rheumatoid Arthritis and Lupus
…p=0.006), and GDM (38.1%; p<0.001), compared to women without one of these diagnoses (11.2%). Pregnancy outcomes in SLE At delivery, women with SLE tender to be older than non-SLE control…
