…individuals with a diagnosis of RA alive in 1998 (when TNF inhibitors were first commercially available). Among these, 6,604 were identified as initiating therapy with a first TNF inhibitor between…
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Selected Topics in Biomedical Science : Monoclonal Antibody
…on the antigen were likely. Frequently this complexity proved unpredictable serological reactions requiring multiple controls to obtain meaningful information. One solution to this issue was to affinity purify a homogenous…
Safety and Efficacy of Leflunomide in Patients with Juvenile Rheumatoid Arthritis (JRA)
…balanced between the two treatment groups. 86 subjects completed the initial 16 weeks of the study. 70 of these entered the blinded extension phase, with 55 of these completing the…
Study Explores the Prevalence of Psoriatic Arthritis Among Individuals with Psoriasis
Treatment of Rheumatoid Arthritis with Anakinra (Kineret®) in combination with Methotrexate
…(Arthritis Rheum 46(3):614-624, 2002) examined the safety and efficacy of anakinra in combination with methotrexate compared to methotrexate alone. Methods: In this study 419 subjects were studied who had moderate-to-severe…
Lost Productive Time and Cost Due to Common Pain Conditions in the US Workforce
…billion dollars are lost due to pain-related conditions that that reduce productivity by compromising performance. Editorial Comments: These results confirm that pain is costly both at the individual and societal…