…to 54 weeks. 29 verified malignancies occurred in the combined TNF inhibitor treated patients, compared to 3 in the placebo group. Included malignancies included solid tumors, hematologic malignancies, and 9…
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The IL-6 Receptor Antagonist Tocilizumab Shows Promise for the Treatment of RA
…treatment-related serious adverse events did appear to be increased in the subjects receiving tocilizumab compared to control. Thirty five of the 359 enrolled subjects (9.7%) experienced a serious treatment-related adverse…
Celecoxib Effective at Reducing Recurrent Colonic Adenomatous Polyps, but May Increase Cardiovascular Risk
…to have higher blood pressure than placebo treated patients. In addition, aspirin treated patients receiving celecoxib demonstrated a trend to higher rates of gastrointestinal ulceration and bleeding. Composite CVD outcomes…
Combining Methotrexate and Leflunomide for the treatment of Rheumatoid Arthritis
…was generally well tolerated clinically. The most common adverse events reported were gastrointestinal (diarrhea, nausea) and respiratory (cough, shortness of breath), and were generally rated as mild to moderate in…
Infliximab (Remicade) in combination with methotrexate, is now indicated for reducing signs and symptoms and inhibiting the progression of structural damage in rheumatoid arthritis patients
…Drug Administration (FDA) for the expanded indication came as a result of radiographic and clinical results from a phase III randomized, double-blind, multi-center trial of 420 adults. (more details on…
Group Exercise, Education, and Combination Self-Management in Women with Fibromyalgia: A Randomized Trial
…and walking speed, while the Medical Outcomes Short-Form-36 was used to evaluate social and emotional function. Finally, depression and self-efficacy were also assessed by questionnaire. Study participants completed the assessments…