Fungal Infections Complicating Therapy with TNFa Antagonists Infliximab and Etanercept TNF-aantagonists (Enbrel®, Remicade®) are effective treatments for rheumatoid arthritis and Crohns disease but also have demonstrated immunosuppressive effects that may…
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Impact of RA Disease Activity and Treatment on the Risk of Developing Lymphoma
…rose sharply (OR 9.4 (95% CI 3.1 28.0) for the 9th decile compared to the first; OR 61.6 (95% CI 21.0 181.0) for the 10th decile compared to the first)….
Swefot Trial Suggests Adding TNF Inhibitor Better than Triple Therapy in RA Patients who do not Rapidly Respond to Methotrexate
…3.2) were then randomized to receive infliximab 3 mg/kg infused using the standard regimen or sulfasalazine (1000 mg twice a day) + hydroxychloroquine (400 mg per day). Efficacy endpoints (EULAR…
European Admixture Associated with Genetic Risk for Rheumatoid Arthritis in African-Americans
Figure: Structure of the MHC Class II Molecule Susceptibility to rheumatoid arthritis (RA) is complex; although a number of genetic susceptibility loci have been identified that appear to confer increased…
Does Survivin and Survivin Antibodies Play a Role in Rheumatoid Arthritis?
…patients compared to non-RA controls. Mean serum IgM anti-survivin antibody levels were significantly higher than synovial anti-survivin antibody levels, and were also significantly higher in RA patients compared to non-RA…
Weight Loss and Exercise Walking Reduce Pain and Improve Physical functioning in Overweight Postmenopausal Women with Knee Osteoarthritis
…6-month intervention. Results: Sixty-three percent of the women (30/48) completed the program. The only difference between completers and non-completers was that the VO2max of the women who did not complete…
