…Mukherjee et al (JAMA 286:954-959, 2001) reviewed several recent published reports on COX-2 agents, as well as data submitted to the US Food and Drug Administration by pharmaceutical companies. The…
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Rheumatologists Enhance Quality of Care for Patients with Rheumatoid Arthritis
…not only for the RA, but for patients’ comorbid conditions as well. These studies emphasize the importance of specialists in improving outcomes for patients with complex conditions such as RA….
Prednisone, but not TNF inhibitors, is associated with an increased risk of serious infection in older RA patients
…of RA therapy with serious infection was modeled, controlling for confounders such as medical comorbidity and RA severity available in the medical claims dataset (i.e. orthopedic procedures, coded extra-articular manifestations…
Chondroitin Sulfate May Act as a Structure Modifying Agent in Knee Osteoarthritis
Severe Medial Compartment Knee OA The efficacy of glucosamine and/or chondroitins in knee osteoarthritis (OA) has been controversial. A recent large, randomized, multicenter trial (the GAIT trial) found no symptomatic…
Excercise and Osteoarthritis
…Relative Physical Activity There was no significant difference in incident OA between subjects reporting higher or lower activity levels compared to peers compared to those reporting similar activity levels. Again,…
Risedronate not an Effective Disease Modifier in Knee Osteoarthritis
…examining the effect of risedronate on symptoms, radiographic progression, and biomarkers of cartilage degradation in symptomatic medial compartment knee OA., Methods The study was conducted at 42 centers in North…
