…Taniguchi et al1 report that rheumatoid synovial fibroblasts differ from osteoarthritis and normal synovial fibroblasts, as well as from skin and lung fibroblasts, in the regulation of a tumor suppressor…
Search Results for: osteoarthritis
Complementary and Alternative Therapies for Arthritis
…The most frequent users of CAM were patients with severe pain, with osteoarthritis and who had a college degree. Patients who most frequently discussed CAM with their physicians were those…
FDA Approves Celecoxib Celebrex
…of osteoarthritis (OA) and adult rheumatiod arthritis (RA). In clinical trials sponsored by G.D. Searle & Co. and Pfizer Inc., Celebrex was shown to be as effective as the nonsteriodal…
Interleukin 17 in Joint Destruction in Rheumatoid Arthritis Patients
…inhibitor of cyclooxygenas-2 (COX-2). The synovial fluids from rheumatoid arthritis patients were found to have significantly higher levels of IL-17 as compared to osteoarthritis patients. Furthermore, using immunostaining, IL-17-positive mononuclear…
Celecoxib Receives FDA Approval as Adjunctive Treatment for FAP
…the treatment of both osteoarthritis and adult rheumatoid arthritis, is the first pharmacologic agent to be indicated to reduce the number of adenomatous colorectal polyps in patients with familial FAP….
Cardiovascular Risk of Selective COX-2 Inhibitors: Fact or Fiction?
…patients with osteoarthritis) 1) Review of Cardiovascular Safety from the Adenoma Prevention with Celecoxib (APC) Trial (reference: Solomon et al. NEJM 2005;352) Methods: The APC trial randomized 2035 men and…