Severe Medial Compartment Knee OA The efficacy of glucosamine and/or chondroitins in knee osteoarthritis (OA) has been controversial. A recent large, randomized, multicenter trial (the GAIT trial) found no symptomatic…
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Prednisone, but not TNF inhibitors, is associated with an increased risk of serious infection in older RA patients
…(PACE) program, a program providing prescription drug coverage to elderly residents with incomes not qualifying for Medicaid. Enrollees from the years 1995 to 2003 with RA were identified and tracked…
Predictors of Increased Carotid Atherosclerosis in RA Patients
…carotid plaque in individuals with RA compared to non-RA controls. Here, Roman et al. (Ann Intern Med 2006; 144:249) confirm this risk for the first time. Methods Adult RA patients…
Osteoporosis Fracture Management
…the injury. The management of vertebral compression fracture is evolving. Vertebroplasty is FDA approved for the management of pain and physical deformity that result from chronic vertebral compression fracture. Studies…
Predictors and Frequency of Infection in RA Patients
The advent of the new biologic therapeutic agents in recent years has increased the concern for opportunistic infections that complicate rheumatoid arthritis (RA). In comparison to the general population, mortality…
Risedronate not an Effective Disease Modifier in Knee Osteoarthritis
…examining the effect of risedronate on symptoms, radiographic progression, and biomarkers of cartilage degradation in symptomatic medial compartment knee OA., Methods The study was conducted at 42 centers in North…