…mechanisms underlying the antiemetic effect of ginger are uncertain. A multicenter, controlled clinical trial of ginger extract for treatment in patients with osteoarthritis (OA) of the knee is currently underway….
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Side Effects of Biologic Medications
No Link Between RA Therapy and Lymphoma Observed in Large Cohort of Rheumatoid Arthritis Patients
…the biologics represented, infliximab was the most frequent (40.3%) followed by etanercept (19.2%) and adalimumab (7.6%). Prednisone was used in 45.7% of subjects at enrollment. Among the RA cohort there…
Comparison of Febuxostat and Allopurinol on Serum Urate Levels
Study results by Moreland, et al comparing febuxostat with allopurinol in Patients with hyperuricemia and gout are now published (N Engl J Med 353: 2505-2507). In this multicenter study, 760…
High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors
…of incident CV events associated with RA was 3.96 [95% confidence interval, 1.86-8.43]. After adjusting for CV risk factors using Poisson regression, the IRR was 3.17 [95% confidence interval, 1.33-6.36]….
Fungal Infections Complicating Therapy with TNFa Antagonists Infliximab and Etanercept.
…infection is combated by macrophage driven cytokines, including TNF-a, and suggests that TNF-ainhibitors could significantly increase the risk of developing histoplasmosis in immunocompromised individuals. Methods: Lee et al (Arthritis &…