…SLE is unknown. In the following study, recently published in the New England Journal of Medicine, mycophenolate mofetil and azathioprine were compared for the maintenance of remission in patients with…
MMF vs AZA for SLE Nephritis
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Impact of Shared Epitope Genes and Smoking on Risk of Seropositive RA Development
…and 246 men) completed questionnaires concerning smoking habits. 66% of RA patients were seropositive for RF near the time of diagnosis. 1,048 controls (736 women and 312 men) completed questionnaires…
Predictors of Increased Carotid Atherosclerosis in RA Patients
…carotid plaque in individuals with RA compared to non-RA controls. Here, Roman et al. (Ann Intern Med 2006; 144:249) confirm this risk for the first time. Methods Adult RA patients…
Association Between Estrogen and COX-2 in Protection from Atherosclerosis
…women. Though this relationship has not been confirmed in humans, recent high profile evidence of increased cardiovascular events associated with several commercially available COX-2 inhibitors is compelling, though sub-analyses by…
Efficacy and Safety of Adalimumab in Patients with Active Ankylosing Spondylitis
…with complete ankylosis met the primary efficacy endpoint, compared to none of the five subjects in the placebo group. In analyses stratified by HLA-B27 status, there was no statistically significant…
Ratio of serum Osteoprotegerin and RANKL predicts radiographic progression in RA
…in the Dutch Combinatietherapie Bij Rheumatoide Artritis (COBRA) trial with baseline and follow-up serum samples. Details of the study methods have been described here previously. Baseline serum levels of RANKL…
