…of RA therapy with serious infection was modeled, controlling for confounders such as medical comorbidity and RA severity available in the medical claims dataset (i.e. orthopedic procedures, coded extra-articular manifestations…
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Predictors of Increased Carotid Atherosclerosis in RA Patients
…carotid plaque in individuals with RA compared to non-RA controls. Here, Roman et al. (Ann Intern Med 2006; 144:249) confirm this risk for the first time. Methods Adult RA patients…
Ability of the PTPN22 1858C/T SNP to Predict RA Development
…is associated with RA. The risk of developing RA is significantly associated with PTPN22 T variant carriage, particularly when in combination with anti-CCP antibodies. Editorial Comment This is an interesting…
Excercise and Osteoarthritis
…Relative Physical Activity There was no significant difference in incident OA between subjects reporting higher or lower activity levels compared to peers compared to those reporting similar activity levels. Again,…
Impact of Shared Epitope Genes and Smoking on Risk of Seropositive RA Development
…and 246 men) completed questionnaires concerning smoking habits. 66% of RA patients were seropositive for RF near the time of diagnosis. 1,048 controls (736 women and 312 men) completed questionnaires…
Ratio of serum Osteoprotegerin and RANKL predicts radiographic progression in RA
…in the Dutch Combinatietherapie Bij Rheumatoide Artritis (COBRA) trial with baseline and follow-up serum samples. Details of the study methods have been described here previously. Baseline serum levels of RANKL…
