…medication must be refrigerated. Do not freeze this medicine. How to inject Golimumab (Simponi®) https://youtu.be/WBJ9ucPxkyc What about side effects? The most common serious side effect is infection. Golimumab can lower the body’s…
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Ustekinumab (Stelara®) Drug Information Sheet
…it? Ustekinumab is injected under the skin (similar to insulin injections) initially, then 4 weeks later, then every 12 weeks. The injections are either 45 mg or 90 mg each,…
Adalimumab (Humira®) Drug Information Sheet
…other malignancies, some fatal, have been reported in children and adolescent patients treated with TNF blockers, including adalimumab. A Federal Drug Administration approved medication guide can be found at: http://www.rxabbvie.com/pdf/humira_medguide.pdf…
RA Pathophysiology
…likely driven by IL-8, leukotriene B4, and possibly localized complement activation through C5a. Neutrophils in the synovial fluid are in an activated state, releasing oxygen-derived free radicals that depolymerize hyaluronic…
Efficacy of Doxycycline Treatment for Knee Osteoarthritis
…in the placebo group were significantly more likely to report > 20% increase in pain in the index knee between 6 month visits compared to the doxycycline group (mean inter-visit…
Brain Centers Responsible for Emotion and Fear Process OA Pain
…between arthritic and experimental pain testing. Despite similar pain ratings, significant differences in location of brain metabolic activity were detected between the three testing conditions. Compared to pain-free testing, arthritic…
