…for ulcer complications, treatment with celecoxib is as effective as treatment with diclofenac plus omeprazole at preventing recurrent gastrointestinal bleeding. Renal adverse events are common with both treatment regimens. Editorial…
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FDA APPROVED: Subcutaneous Abatacept for the Treatment of Rheumatoid Arthritis
…were comparable between the two groups. The proportion of patients in each group with improvements in HAQ-DI was comparable (68.2% subcutaneous vs 63.8% intravenous). The safety profile was also similar…
Intravenous Zoledronic Acid in Postmenopausal Women with Low Bone Mineral Density
…the femoral neck, bone markers in the zoledronic acid groups were increased 3.1-3.5% as compared to the placebo group (P<0.001). Biochemical markers of bone resorption were comparably suppressed in all…
Zolendronic Acid (Reclast®)
…24-48 hours and usually occurs only after the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. Less common side…
Are TNF Inhibitors Efficacious for the Treatment of Sciatica?
…Conclusions Compared to placebo, two injections of adalimumab improved back pain, reduced the need for surgery, and (to a smaller extent) reduced leg pain associated with acute sciatica. Editorial Comment…
Denosumab Receives Approval Recommendation for the Treatment of Post-Menopausal Osteoporosis
On June 2, 2010, the Advisory Committee for Reproductive Health Drugs of the U.S. Food and Drug Administration recommended approval of denosumab, which will be marketed under the trade-name Prolia,…
