…treated with estradiol or placebo. Cultures of bone marrow monocytes (BMM) from OVX athymic mice did not have increased osteoclast formation when compared with sham athymic mice. In the control…
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Decorin Deficient Mice Show Resistance to Lyme Disease News Summary from Johns Hopkins Arthritis
…dissemination of Borrelia in joints, heart, bladder and ear tissues. The percent of positive cultures for Borrelia was significantly reduced in Dcn -/- mice compared to Dcn +/- and Dcn…
Transcription of several genes associated with antigen-induced anergy are regulated by rheumatoid arthritis synovial T cells News Summary from Johns Hopkins Arthritis
…compared to an anergic T-cell clone and to T-cells from reactive arthritis (ReA) patients in which no activation defect is known. Transcription of anergy-related transcripts was compared in synovial tissue…
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…of Washington School of Public Health and Community Medicine, Department of Epidemiology M.B.A.: Medical Services Management, Johns Hopkins University School of Professional Studies in Business and Education Internship and Residency:…
Intraarticular Injection of Infliximab not Effective in Patients with Inflammatory Arthritis
…effective. In total, none of the 20 injections of infliximab were deemed effective, compared to 8 of the 21 injections of methylprednisolone (38%; p=0.004 compared to infliximab). Time to failure…
Are TNF Inhibitors Efficacious for the Treatment of Sciatica?
…Conclusions Compared to placebo, two injections of adalimumab improved back pain, reduced the need for surgery, and (to a smaller extent) reduced leg pain associated with acute sciatica. Editorial Comment…
