…is 24.4 cases per 100,000 compared to a background rate of 6.2 cases per 100,000 among RA patients not treated with infliximab (Urbansky, et al. Arthritis Rheum. In press). Conclusion:…
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CTLA4Ig Shows Promise in the Treatment of RA
…be considered high, despite concurrent methotrexate. Eighty patients discontinued the study prior to completion, half of whom were from the placebo group. Most discontinued because of lack of efficacy. The…
In Crohns disease, the development of antibodies to infliximab (Remicade) is associated with shorter duration of clinical response and more infusion reactions.
…evaluated before and after each infusion. Concentrations of infliximab and antibodies to infliximab were assayed at each visit and before each infusion by commercial ELISA. Concentrations of infliximab below 1.4…
Risk of Recurrent Gastrointestinal Bleeding in Patients Taking Celecoxib
…for ulcer complications, treatment with celecoxib is as effective as treatment with diclofenac plus omeprazole at preventing recurrent gastrointestinal bleeding. Renal adverse events are common with both treatment regimens. Editorial…
FDA APPROVED: Subcutaneous Abatacept for the Treatment of Rheumatoid Arthritis
…response at month 6. ACR 50, ACR 70, and HAQ-DI (also at month 6) were secondary endpoints. Safety assessments were completed regularly for both groups and included injection site reactions…
Disease Outcomes of Early Non-Radiographic Spondyloarthropathy Explored
…age of onset did not differ according to whether the patient has AS or non-radiographic SpA. Conclusions Compared to those with AS of comparable disease duration, those with non-radiographic SpA,…
