…stress. This effect was found to be mediated through estrogen receptor. Treatment of ovariectomized LDLR KO and wild-type mice with estrogen resulted in increased prostacyclin synthesis and decreased lipid peroxidation….
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Parathyroid Hormone Decreases the Risk of Fractures in Postmenopausal Women with Osteoporosis News Summary from Johns Hopkins Arthritis
…months, respectively. Participants in all three groups received equivalent daily doses of calcium and vitamin D. The study was stopped by the sponsor (Eli Lilly and Company) due to reports…
Ability of the PTPN22 1858C/T SNP to Predict RA Development
…of RA. Methods Samples were derived from an established population-based blood sample repository, the Medical Biobank of Northern Sweden. Early RA patients diagnosed at the University Hospital, Umea, Sweden who…
Osteoporosis Fracture Management
…patient focused assessment of ischemia; pain control, and prevention of common complications such as delirium, deep venous thrombosis, pulmonary emboli, infections, incontinence, constipation, depression, anemia, and pressure sores. Physical and…
TNF Inhibitor Use Associated with a Reduced Risk of Myocardial Infarction in Rheumatoid Arthritis Patients?
…in the TNF inhibitor cohort and 1.34 years in the DMARD cohort. During follow-up, 63 verified MIs were reported in the TNF inhibitor cohort (4.8 per 1000 person-years) compared to…
Vertebroplasty not Superior to Placebo for the Treatment of Painful Osteoporotic Fractures
…similar to the one described above. Patients were evaluated at baseline, and at days 3, 14, and 90. The primary outcomes were disability (based on a modified version of the…