…the femoral neck, bone markers in the zoledronic acid groups were increased 3.1-3.5% as compared to the placebo group (P<0.001). Biochemical markers of bone resorption were comparably suppressed in all…
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Long-term structural benefits from short-term aggressive treatment of early rheumatoid arthritis
…that treatment with combinations of DMARDs is superior to treatment with sequential single DMARDs in suppressing disease activity and slowing destruction of the joints. One such report from the Combinatietherapie…
Zolendronic Acid (Reclast®)
…24-48 hours and usually occurs only after the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. Less common side…
Targeting Interleukin-17 Studied in Rheumatoid Arthritis
…the most common treatment-related adverse events. In Part B, adverse events were uncommon –with leukopenia being the most common and observed in 7%. Neutrophil counts <1,500 were observed in 5…
Denosumab Receives Approval Recommendation for the Treatment of Post-Menopausal Osteoporosis
On June 2, 2010, the Advisory Committee for Reproductive Health Drugs of the U.S. Food and Drug Administration recommended approval of denosumab, which will be marketed under the trade-name Prolia,…
Estrogen Deficiency Induces Bone Loss by Enhancing T Cell Production of TNF alpha news summary by Johns Hopkins Arthritis
…treated with estradiol or placebo. Cultures of bone marrow monocytes (BMM) from OVX athymic mice did not have increased osteoclast formation when compared with sham athymic mice. In the control…
