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Ratio of serum Osteoprotegerin and RANKL predicts radiographic progression in RA
…in the Dutch Combinatietherapie Bij Rheumatoide Artritis (COBRA) trial with baseline and follow-up serum samples. Details of the study methods have been described here previously. Baseline serum levels of RANKL…
TNF Inhibitor Use Associated with a Reduced Risk of Myocardial Infarction in Rheumatoid Arthritis Patients?
…registry of patients initiated on biologic therapy in the UK with a parallel comparison cohort of non-TNF inhibitor treated patients enrolled. Participants undergo a comprehensive baseline assessment and follow-up assessments…
Barriers to Urate Lowering Therapy Explored
…lack of tophi. Receiving first prescription of urate lowering therapy from a specialist was also associated with longer persistence of therapy. Conclusions Poor adherence and extended discontinuation were common with…
Osteoarthritis: Pathophysiology
…compressive properties which are imparted by its extracellular matrix, composed predominantly of type II collagen and proteoglycans. Under normal conditions, this matrix is subjected to a dynamic remodeling process in…
Methotrexate Injection
…medicine. This includes prescription and non-prescription medicines as well as birth control pills, vitamins, and herbal supplements. Methotrexate can be taken with other medications. You should not take methotrexate while…
