…if you are: Thin Do not exercise Smoke Drink alcohol often Caucasian Do not get enough calcium or vitamin D Going through or past menopause Have a family history of…
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Targeting Interleukin-17 Studied in Rheumatoid Arthritis
…patients, all receiving study drug; however, there were no study discontinuations due to neutropenia. Infections were not more common in patients receiving study drug compared to placebo. One serious adverse…
Transcription of several genes associated with antigen-induced anergy are regulated by rheumatoid arthritis synovial T cells News Summary from Johns Hopkins Arthritis
…response to antigens and mitogens. Using differential display RT-PCR, Ali et al (J Clin Inv 107:519,2001) examined the levels of differentially expressed transcripts in RA and as a control, T-cells…
Denosumab Receives Approval Recommendation for the Treatment of Post-Menopausal Osteoporosis
Decorin Deficient Mice Show Resistance to Lyme Disease News Summary from Johns Hopkins Arthritis
…throughout the body. Using decorin-deficient mice (Dcn -/-), Brown, et al (J Clin Inv 107:845, 2001) examined the role of decorin in the development of LD. Cultures of blood and…
Are TNF Inhibitors Efficacious for the Treatment of Sciatica?
…Conclusions Compared to placebo, two injections of adalimumab improved back pain, reduced the need for surgery, and (to a smaller extent) reduced leg pain associated with acute sciatica. Editorial Comment…