…role of T cells in ovariectomy-induced bone loss. Studies were done in athymic nude mice (T cell deficient) and control littermates. Animals were either sham operated or ovariectomized (OVX), and…
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Does early treatment of rheumatoid arthritis produce long-lasting benefits?
…first year with use of DMARD therapy in early rheumatoid arthritis compared to the pyramid approach is not sustained if aggressive DMARD therapy is not maintained. Editorial Comments: At first…
Anakinra (Kineret®) Drug Information Sheet
…treating RA, the dose is 100mg per day as an injection under the skin. The drug should be injected at around the same time every day. If you miss a…
Efficacy of knee tape in the management of osteoarthritis of the knee
…thought to relieve pain by improving joint alignment and unloading inflamed soft tissue. Hinman and colleagues (British Medical Journal 2003; 327: 135-141) conducted a randomized controlled clinical trial to investigate…
Tidal Irrigation is not an effective Treatment for Knee Osteoarthritis
…studies were both adequately powered and placebo controlled. To address this issue, Bradley et al (Arthritis Rheum 46:100-108, 2002) developed a sham modification of the needle tide irrigation procedure and…
Osteoarthritis: Pathophysiology
…compressive properties which are imparted by its extracellular matrix, composed predominantly of type II collagen and proteoglycans. Under normal conditions, this matrix is subjected to a dynamic remodeling process in…