…the pain, stiffness, and fatigue that characterized fibromyalgia make exercising consistently a challenge. In this review article, the potential value of exercise and physical activity as treatment for patients with…
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Pfizer Releases Statement on Cardiovascular Safety of Celecoxib (Celebrex)
…and non-fatal cardiovascular events compared to patients receiving placebo. Based on this review, dosing of celecoxib was halted for this trial. An identical review by the same DSMB of the…
FDA Arthritis Advisory Board Recommends the Approval of Tocilizumab (Actemra) for the Treatment of RA
Figure: Tocilizumab prevents binding of IL-6 with its receptor On July 29, 2008, the Arthritis Advisory Board of the FDA reviewed the new Biologics License Application for tocilizumab, which will…
Zolendronic Acid (Reclast®)
…24-48 hours and usually occurs only after the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. Less common side…
Disease Outcomes of Early Non-Radiographic Spondyloarthropathy Explored
…age of onset did not differ according to whether the patient has AS or non-radiographic SpA. Conclusions Compared to those with AS of comparable disease duration, those with non-radiographic SpA,…
CTLA4Ig Shows Promise in the Treatment of RA
…IgG1, works by binding CD80 and CD86 on antigen presenting cells. Preventing this binding blocks the engagement of CD28, a sequence of co-stimulatory events required for optimal activation of T…