…age of onset did not differ according to whether the patient has AS or non-radiographic SpA. Conclusions Compared to those with AS of comparable disease duration, those with non-radiographic SpA,…
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CTLA4Ig Shows Promise in the Treatment of RA
…IgG1, works by binding CD80 and CD86 on antigen presenting cells. Preventing this binding blocks the engagement of CD28, a sequence of co-stimulatory events required for optimal activation of T…
Ibandronate Sodium (Boniva®)
…the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. Less common side effects may be pain or trouble swallowing,…
Zolendronic Acid (Reclast®)
…24-48 hours and usually occurs only after the first injection. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. Less common side…
Transcription of several genes associated with antigen-induced anergy are regulated by rheumatoid arthritis synovial T cells News Summary from Johns Hopkins Arthritis
…compared to an anergic T-cell clone and to T-cells from reactive arthritis (ReA) patients in which no activation defect is known. Transcription of anergy-related transcripts was compared in synovial tissue…
Targeting Interleukin-17 Studied in Rheumatoid Arthritis
…the most common treatment-related adverse events. In Part B, adverse events were uncommon –with leukopenia being the most common and observed in 7%. Neutrophil counts <1,500 were observed in 5…