…for ulcer complications, treatment with celecoxib is as effective as treatment with diclofenac plus omeprazole at preventing recurrent gastrointestinal bleeding. Renal adverse events are common with both treatment regimens. Editorial…
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FDA APPROVED: Subcutaneous Abatacept for the Treatment of Rheumatoid Arthritis
…were comparable between the two groups. The proportion of patients in each group with improvements in HAQ-DI was comparable (68.2% subcutaneous vs 63.8% intravenous). The safety profile was also similar…
Intravenous Zoledronic Acid in Postmenopausal Women with Low Bone Mineral Density
…the femoral neck, bone markers in the zoledronic acid groups were increased 3.1-3.5% as compared to the placebo group (P<0.001). Biochemical markers of bone resorption were comparably suppressed in all…
Are TNF Inhibitors Efficacious for the Treatment of Sciatica?
…Conclusions Compared to placebo, two injections of adalimumab improved back pain, reduced the need for surgery, and (to a smaller extent) reduced leg pain associated with acute sciatica. Editorial Comment…
Targeting Interleukin-17 Studied in Rheumatoid Arthritis
…the most common treatment-related adverse events. In Part B, adverse events were uncommon –with leukopenia being the most common and observed in 7%. Neutrophil counts <1,500 were observed in 5…
Are the Incidence and Prevalence of RA Changing in the United States?
…after diagnosis. Compared to prior periods, smoking in men, but not women, had decreased from the 1985-1994 period. The demographic adjusted incidence rate for RA was 41 per 100,000 (95%…