…dissemination of Borrelia in joints, heart, bladder and ear tissues. The percent of positive cultures for Borrelia was significantly reduced in Dcn -/- mice compared to Dcn +/- and Dcn…
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Estrogen Deficiency Induces Bone Loss by Enhancing T Cell Production of TNF alpha news summary by Johns Hopkins Arthritis
…treated with estradiol or placebo. Cultures of bone marrow monocytes (BMM) from OVX athymic mice did not have increased osteoclast formation when compared with sham athymic mice. In the control…
Arthritis Research
…is often marked by flares and remissions or times when symptoms are more pronounced, then dissipate. Common complaints are joint pain and generalized stiffness throughout the day, joints that may…
Long-term structural benefits from short-term aggressive treatment of early rheumatoid arthritis
…that treatment with combinations of DMARDs is superior to treatment with sequential single DMARDs in suppressing disease activity and slowing destruction of the joints. One such report from the Combinatietherapie…
Are TNF Inhibitors Efficacious for the Treatment of Sciatica?
…Conclusions Compared to placebo, two injections of adalimumab improved back pain, reduced the need for surgery, and (to a smaller extent) reduced leg pain associated with acute sciatica. Editorial Comment…
Denosumab Receives Approval Recommendation for the Treatment of Post-Menopausal Osteoporosis
On June 2, 2010, the Advisory Committee for Reproductive Health Drugs of the U.S. Food and Drug Administration recommended approval of denosumab, which will be marketed under the trade-name Prolia,…
