…women. Though this relationship has not been confirmed in humans, recent high profile evidence of increased cardiovascular events associated with several commercially available COX-2 inhibitors is compelling, though sub-analyses by…
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Are TNF Inhibitors Efficacious for the Treatment of Sciatica?
…balanced on baseline characteristics. All of the patients allocated to adalimumab, and 26 allocated to placebo completed the study. Leg pain improved with time in both groups; however, there were…
Risk of Recurrent Gastrointestinal Bleeding in Patients Taking Celecoxib
…for ulcer complications, treatment with celecoxib is as effective as treatment with diclofenac plus omeprazole at preventing recurrent gastrointestinal bleeding. Renal adverse events are common with both treatment regimens. Editorial…
Effect of Rofecoxib on Renal Function is Similar to Nonselective NSAIDS
…two- part study comparing effects on renal function in patients receiving rofecoxib or indomethacin. Glomerular filtration rate, creatinine clearance and urinary and serum sodium and potassium levels were assessed. Patients…
American College of Rheumatology Comments on Zinaxin
…registered trade name for a commercially available ginger root extract. The ACR points out that there are no controlled published research data that prove that Zinaxin or other ginger root…
Disease Outcomes of Early Non-Radiographic Spondyloarthropathy Explored
…is the largest study, to date, comparing disease features in the early spondyloarthropathies. One of the most interesting findings revealed by the study is a lack of a difference in…