…to work slower, changing the number of days worked, and coordinating overtime. Other noted adaptations included increased use of disease modifying anti-rheumatic drugs (27%), use of a transportation service (23%),…
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Interaction of environment, genetics and autoimmunity in the pathogenesis of rheumatoid arthritis (RA)
…dependent manner; The combination of a positive smoking history and double copies of the shared epitope genes increased the risk for RA 21-fold compared to the risk for nonsmokers carrying…
Effect of Muscle-Derived Stem Cells on Cartilage Repair
…setting of sustained injury. Current methods to repair damaged articular cartilage, including transplants of cartilage and bone, have had limited success due to a lack of durability and sustainability of…
Adalimumab is Safe and Efficacious as Monotherapy in Patients with Rheumatoid Arthritis
Arthritis News – 2004 Adalimumab is Safe and Efficacious as Monotherapy in Patients with Rheumatoid Arthritis In patients with rheumatoid arthritis (RA) who failed prior DMARD therapy, van de Putte…
Does an imbalance of mechanical forces across the knee promote osteoarthritis?
…the lower extremities of patients during walking trials. Validated models were used to determine normalized joint reaction forces at the medial and lateral knee compartments. Results: At the time of…
T Cell Blockade Appears to be Efficacious in the Treatment of Rheumatoid Arthritis
…mg/kg of CTLA-4Ig or LEA29Y. All disease modifying anti-rheumatic drug (DMARDS) were discontinued 28 days prior to baseline, but stable doses of corticosteroids (< 10 mg/day) and non-steroidal anti-inflammatory drugs…