…screen for latent TB. Tuberculin skin testing with purified protein derivative (PPD) is commonly used as a screen for TB before the initiation of TNFα inhibitors; although imperfections in the…
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FDA Approves Kineret for Treatment in Rheumatoid Arthritis
…Kineret can be used alone or in combination with other DMARDs, but should not be used with the tumor necrosis factor blocking agents, etanercept and infliximab. In clinical trials, most…
Acetaminophen, aspirin, and chronic renal failure
…of aspirin and acetaminophen. Results: Aspirin was used regularly by 37% of the patients with renal failure and by 19% of the controls. Acetaminophen was used regularly by 25% of…
Corticosteroids Linked to Cardiovascular Events in Rheumatoid Arthritis
…combined CV outcome. Conclusions Corticosteroid use was associated with CV events in RA in a dose dependent manner. The risk was highest for RF seropositive patients. Editorial Comments The findings…
Novel Genetic Susceptibility Locus for Rheumatoid Arthritis identified from a Genome-Wide Association Study
…CI 0.93 – 1.32) compared to 1.37 (95% CI 1.18 – 1.58) in the North American population. However, combining the population resulted in an odds ratio of 1.32 (95%CI 1.23…
Ustekinumab, an Inhibitor of IL 12/23, Studied in Patients with Psoriatic Arthritis
…received ustekinumab in the cross-over phase. A total of 63 of the patients who initially received ustekinumab completed through week 36 while 52 of the initially placebo treated patients completed…