…Chines etal (Arthritis & Rheumatism 42:2309, 1999), in a 12-month, randomized, placebo-controlled, double-blind, multicenter trial, examined the safety and efficacy of risedronate as a preventative therapy for corticosteroid-induced bone loss….
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Does Antioxidant Intake Protect Against the Development of Rheumatoid Arthritis or Lupus?
…or SLE according to level of intake of any individual antioxidants (vitamins A, C, E, α-carotenoid, β-carotene, β-cryptoxanthine, or leutein) either from dietary sources, supplements, or combined, in crude analyses…
Clinical Trials of Hyaluronic Acid Reflect Significant Publication Bias
…than 50% dropout rate. Inclusion of an intra-articular placebo control and utilization of validated knee pain assessment scales were required. Intent-to-treat analyses (or completers-only analyses with no dropouts) were separately…
HMGB-1 Plays a Role in the Pathogenesis of Arthritis from Johns Hopkins Arthritis
…NMRI, C57BL/6, and CB17. When measured 7 days after injection of 5 mg rHMGB-1, joint inflammation occurred in 80% of CB17I mice, 79% of NMRi mice, and 40% of C57BL/6…
Relationship Between Body Weight Gain and Significant Knee, Hip, and Back Pain in Among Older Americans
…weight (18.5-24.9), overweight (25-29.9), obese class I (30-34.9), obese class II (35-39.9), and obese class III (> 40). The presence of significant knee, hip, and back pain was reported by…
Tumor Necrosis Factor (TNF) is not Necessary for the Development of Severe Inflammatory Arthritis News Summary from Johns Hopkins Arthritis
…TNF. To examine this question, Campbell et al (J. Clin. Invest. 107:1519-1527, 2001) examined a strain of mouse in which TNF was “knocked out” (Tnf-/-). Chronic inflammatory arthritis was induced…