…their disease and treatment affect disability and every day function. Patient centered outcome questionnaires are commonly used to assess and monitor HRQL. HRQL measures are increasingly being used in North…
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Decorin Deficient Mice Show Resistance to Lyme Disease News Summary from Johns Hopkins Arthritis
…dissemination of Borrelia in joints, heart, bladder and ear tissues. The percent of positive cultures for Borrelia was significantly reduced in Dcn -/- mice compared to Dcn +/- and Dcn…
Transcription of several genes associated with antigen-induced anergy are regulated by rheumatoid arthritis synovial T cells News Summary from Johns Hopkins Arthritis
…compared to an anergic T-cell clone and to T-cells from reactive arthritis (ReA) patients in which no activation defect is known. Transcription of anergy-related transcripts was compared in synovial tissue…
Targeting Interleukin-17 Studied in Rheumatoid Arthritis
…the most common treatment-related adverse events. In Part B, adverse events were uncommon –with leukopenia being the most common and observed in 7%. Neutrophil counts <1,500 were observed in 5…
Estrogen Deficiency Induces Bone Loss by Enhancing T Cell Production of TNF alpha news summary by Johns Hopkins Arthritis
…treated with estradiol or placebo. Cultures of bone marrow monocytes (BMM) from OVX athymic mice did not have increased osteoclast formation when compared with sham athymic mice. In the control…