…throughout the body. Using decorin-deficient mice (Dcn -/-), Brown, et al (J Clin Inv 107:845, 2001) examined the role of decorin in the development of LD. Cultures of blood and…
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Optimal Colchicine Dosage for Acute Gout Explored
High Intakes of Vitamin A May Increase the Risk of Fracture
…converted to retinoic acid, which suppresses osteoblast activity and stimulates osteoclast formation in vitro. In a population-based, 30-year longitudinal study, Michaelsson et al use a biological marker of vitamin A,…
Improved Cardio-Respiratory Fitness with Prescribed Exercise
…Four-hundred and ninety-two sedentary adults were randomized to one of five study conditions: moderate-intensity/low frequency; hard-intensity/low frequency; moderate-intensity/high frequency; hard-intensity/high frequency; and a comparison group that received physician advice and…
Are the Incidence and Prevalence of RA Changing in the United States?
…from disease. Here, Myasoedova et al (Arthritis Rheum 2010; 62(6): 1576) explore the trends in RA incidence and prevalence over 50 years in a population-based cohort study conducted in Olmsted…
In Crohns disease, the development of antibodies to infliximab (Remicade) is associated with shorter duration of clinical response and more infusion reactions.
…infliximab, and infusion-related side effects in patients with Crohns disease. Methods: The study cohort consisted of 125 consecutive patients with Crohns disease who were treated with infliximab 5 mg/kg. Patients…