…monotherapy or in combination with methotrexate. Editorial Comment Based largely on the results of this study (known as ADEPT – Adalimumab Effectiveness in Psoriatic Arthritis Trial) adalimumab was approved by…
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Efficacy of Intramuscular (IM) Methotrexate in the Treatment of RA
…certain patients sparing the need to shift to alternate DMARDS or to introduce the cost and potential toxicities of combination regimens. Here, Lambert et al (Arthritis Rheum 50(2):364, 2004) examine…
Manual Therapy, Physical Therapy, or Continued Care by a General Practitioner for Patients with Neck Pain
…disabling condition. A variety of therapies are commonly prescribed for neck pain, however these methods have never been directly compared. Hoving et al (Ann Intern Med 2002;136:713-722) conducted a randomized,…
Arthroscopic Surgery is No Better than Placebo (Sham Surgery) in Treating the Pain and Dysfunction of Osteoarthritis of the Knee
…completed the 2-year study. Since this study was performed at a Veterans Hospital, 93% of participants were male. Sixty percent of participants were white and approximately 30% were black. Neither…
Reduced Disability at Five Years with Early Treatment of Inflammatory Polyarthritis News Summary from Johns Hopkins Arthritis
…in the short-term. Early aggressive treatment of RA is recommended based on short-term study results but there are only sparse data documenting longer term outcomes. The cost of long-term clinical…
Osteopathic Spinal Manipulation for Low Back Pain
…utilizes manual therapy in combination with standard treatment methods, and focuses on the need to optimize blood circulation to maintain and restore health. Leurgans, etal (N Engl J Med 341:1426,…