…partially due to difficulties in tracking and quantifying specific exposures within complex frameworks, particularly when exposure likely precedes onset of disease by years or even decades. Here, Gold et al…
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T Cell Blockade Appears to be Efficacious in the Treatment of Rheumatoid Arthritis
…patients completed follow up through day 85, and 160 patients completed follow up through day 169. The most common reason for discontinuation of the protocol was worsening arthritis; discontinuation frequencies…
Efficacy of Intramuscular (IM) Methotrexate in the Treatment of RA
…certain patients sparing the need to shift to alternate DMARDS or to introduce the cost and potential toxicities of combination regimens. Here, Lambert et al (Arthritis Rheum 50(2):364, 2004) examine…
Large Study of Acute Back Pain Demonstrates Rarity of Serious Pathology
Association Between Treatment with Infliximab and the Development of Tuberculosis News Summary from Johns Hopkins Arthritis
…these protective responses. That etanercept does not appear to carry the same risk for TB may be explained by the lower stability of its complexes with TNF, compared to infliximab….
A Reappraisal of HAQ Disability in Rheumatoid Arthritis (RA)
…standard in RA and is routinely used in clinical trials. The Health Assessment Questionnaire (HAQ) is the most common assessment tool for functional disability, and is a 20-item questionnaire in…