…treated with prophylactic doses of heparin and a baby aspirin during the next pregnancy. Several clinical trials have indicated that the combination of heparin and aspirin is likely preferable to…
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Do TNF Inhibitors Increase the Risk of Heart Failure in Rheumatoid Arthritis?
The observation that TNF-α is elevated in individuals with advanced heart failure (HF) prompted several high-profile clinical trials investigating whether TNF inhibitors could be used to treat HF. The failure…
Ankylosing Spondylitis
…anterior uveitis. Cardiac involvement resulting in aortitis and arrhythmias occur less commonly. Spinal inflammation results in symptoms of back stiffness, soreness, and pain. Symptoms tend to worsen in the early morning hours, causing sleep…
Glucosamine Sulphate for the Treatment of Osteoarthritis News Summary from Johns Hopkins Arthritis
…knee was used as a surrogate measure of cartilage integrity, and the Western Ontario McMaster Arthritis Scale (WOMAC) was used to assess symptoms. Measurements were taken at baseline, 1, and…
Lower Dose of Rituximab for RA Treatment Explored
The dosage of rituximab commonly used in clinical practice (1000 mg infused twice, separated by two weeks) is largely empirically based. It is unclear whether lower doses will result in…
Leptin, a hormone that regulates fat, also regulates bone formation
…are used extremely commonly for management of high blood pressure and congestive heart failure. That these agents could also promote new bone formation introduces an entire new therapeutic area of…