…(RA). In the mice, the arthritis is sustained by autoantibodies to glucose-6-phosphate isomerase (GPI) and the arthritis can be induced in nave mice by transfer of serum. In this study,…
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The Natural History of the Development of Obesity in a Cohort of Young U.S. Adults between 1981 and 1998
…for Hispanic women compared to white women. For men, obesity developed 2.5 times faster among Hispanic men compared to white men. After the age of 28, black men developed obesity…
RA Sera Show No Specificity for Antibodies to Glucose-6-Phosphate Isomerase
…this study. Specifically, no clear prevalence or specificity of anti-GPI antibodies was found in patients with RA. Editorial Comment: These data contradict the results published in 2001 by Schaller et…
Coffee Consumption May Protect Against the Development of Gout
…problems. Here, Choi et al (Arthritis Rheum 2007; 56(6): 2049) explore whether coffee consumption affects the risk of incident gout in men enrolled in the Health Professionals Follow-up Study. Methods…
Ocrelizumab, a Humanized Anti-CD20 Monoclonal Antibody, Studied for the Treatment of RA
Immunization Responses with Rituximab Explored
…to mount a response, there was no clear-cut relationship between peripheral B-cell constitution and vaccine response. Editorial Comment These two studies, although differing in quality, are complementary. RA patients, particularly…