…to determine whether celecoxib, a COX-2 specific inhibitor, is associated with a lower incidence of serious upper gastrointestinal (UGI) ulcer complications compared with conventional nonsteroidal anti-inflammatory drug (NSAIDs). Serious UGI…
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Anakinra (Kineret) is Safe and Well Tolerated in RA Patients with Comorbid Conditions from Johns Hopkins Arthritis
…study, Fleischmann et al (Arthritis Rheum 48:927, 2003) evaluated the safety and efficacy of anakinra in patients with and without comorbid conditions and in combination with conventional DMARDs. The preliminary…
Apremilast (Otezla) approved by FDA
…(methotrexate ≤ 25 mg weekly, leflunomide ≤ 20 mg daily, or sulfasalazine ≤ 2000 mg daily), corticosteroids (prednisone ≤ 10 mg daily equivalent), and NSAIDs were permitted. However, co-treatment with…
Study Suggests that Genes and Environment Influence the Risk of Developing Rheumatic Disease
…risk compared to the native Swedish population were lost in the offspring of immigrants, suggesting that environmental factors also influence the risk of developing rheumatic disease. Editorial Comment This is…
High Disease Activity During Pregnancy Associated with Lower Birth Weight
…RA group compared to comparison cohorts. Caesarian delivery was more frequent in women with moderate to high RA disease activity during the third trimester compared to women with low disease…
Leflunomide and Pregnancy Outcomes Explored
…mother was electively terminated. Among the live births, delivery by cesarean section was significantly more common among leflunomide exposed mothers (48%) compared to disease-matched non-exposed mothers (29%) or healthy control…
