…treatment options available, this course offers clinicians information about the strategies for early accurate differential diagnosis and opportunities to learn about the establishing an effective, comprehensive treatment plan, utilizing multiple…
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Febuxostat Submitted for FDA Approval in Chronic Gout
…uric acid in subjects with gout and hyperuricemia compared to allopurinol 300 mg per day. Safety of both doses of febuxostat was comparable to allopurinol, currently the only approved treatment…
Risk Factors for Bisphosphonate Associated Jaw Osteonecrosis
Gastrointestinal complications, including esophageal mucosal ulceration, are the most frequent complications of bisphosphonate therapy, commonly used to treat osteoporosis, metabolic bone diseases (such as Pagets disease), multiple myeloma, and to…
Non-Steroidal Anti-inflammatory Drugs Information Sheet
…are many NSAIDS on the market, available by prescription or over the counter. Some common names are Motrin®, Advil®, Aleve®, Voltaren®, Indocin®, aspirin. NSAIDS help with symptoms of rheumatoid arthritis…
High Normal Serum Uric Acid Levels May Lead to Ischemic Changes in the Brain
…revealed that the association was similar in men and women, strongest in older subjects (age 60+), and was maintained even when subjects with competing comorbidities (i.e. severe health problems, dementia,…
Interleukin-18 Acts as a Proinflammatory Stimulus in Rheumatoid Arthritis
…clones. Gracie, et al (J Clin Invest 104:1393-1401, 1999) examined the role of IL-18 in promoting rheumatoid synovitis. Using RT-PCR significantly higher levels of IL-18 mRNA and protein were detected…