Inflimab, In Combination with Methotrexate, is Indicated for Inhibition of Progression of Structural Damage in RA Patients Infliximab (Remicade®), in combination with methotrexate, is now indicated for reducing signs and…
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Combining Methotrexate and Leflunomide for the treatment of Rheumatoid Arthritis
…leflunomide, 10-20 mg/day. Patients were evaluated for adverse effects as well as clinical responses using the ACR 20 response criteria. Twenty-three patients completed 1 year of treatment. The combination therapy…
Celecoxib Effective at Reducing Recurrent Colonic Adenomatous Polyps, but May Increase Cardiovascular Risk
…1.1 6.1) for celecoxib 400 mg per day compared to placebo and 3.4 (95% CI 1.5 7.9) for celecoxib 800 mg per day compared to placebo. In the PreSAP trial,…
Study Demonstrates Promise for Spleen Tyrosine Kinase (Syk) Inhibitors for the Treatment of Rheumatoid Arthritis
…efficacy compared to placebo in a short term study of RA patients on background methotrexate. Here, Weinblatt et al (NEJM 2010; published online ahead of print on September 22, 2010)…
Side Effects of Biologic Medications
…body rash for injections. Less common side effects can include: Central nervous system symptoms such as sudden vision problems, or any new numbness or tingling. Cardiac reactions including sudden swelling…
Association Between Lower Extremity Muscle Mass and Knee Cartilage Volume
…a well-established risk factor for the development of knee OA. However, weight alone may not completely identify risk, as body weight reflects distribution of body composition (adipose, lean tissue mass,…
