…advisory committee. Febuxostat is similar to the most commonly used urate lowering agent, allopurinol, in that it inhibits xanthine oxidase, an important intermediate in the production of uric acid. However,…
…the lateral compartment. In terms of progression of knee OA, of the 39 knees demonstrating progressive joint space narrowing (JSN) of the medial compartment, 27 (69.2%) had medial bone marrow…
…individuals with a diagnosis of RA alive in 1998 (when TNF inhibitors were first commercially available). Among these, 6,604 were identified as initiating therapy with a first TNF inhibitor between…
Study results by Moreland, et al comparing febuxostat with allopurinol in Patients with hyperuricemia and gout are now published (N Engl J Med 353: 2505-2507). In this multicenter study, 760…
…and reductions in vertebral compression fractures are comparable to alendronate.(ref 24) Side Effects: Gastrointestinal are most common, especially nausea, acid reflux symptoms, and constipation. To maximize absorption, should be taken…
…57* Fostamatanib 100 mg BID 36* 67* * p<0.05 compared to placebo There were 21 withdrawals from the study due to adverse events (15 from the active treatment groups). Adverse…
